USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: SMD3_HUMAN USC-OGP 2-DE database:  SMD3_HUMAN SMD3_HUMAN General information about the entry View entry in simple text format Entry name SMD3_HUMAN Primary accession number P62318 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Small nuclear ribonucleoprotein Sm D3; Short=Sm-D3; AltName: Full=snRNP core protein D3;. Gene name Name=SNRPD3 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1338: pI=5.68; Mw=15649 SPOT OGP-1339: pI=5.56; Mw=15578 Cross-references UniProtKB/Swiss-Prot P62318; SMD3_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SMD3_HUMAN Primary accession number P62318 Secondary accession number(s) B4DJP7 B5BU13 P43331 Sequence was last modified on  July 5, 2004 (version 1) Annotations were last modified on  March 15, 2017 (version 142) Name and origin of the protein Description RecName: Full=Small nuclear ribonucleoprotein Sm D3; Short=Sm-D3; AltName: Full=snRNP core protein D3; Gene name Name=SNRPD3 Encoded on Name=SNRPD3 Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Methylation; mRNA processing; mRNA splicing; Nucleus; Reference proteome; Repeat; Ribonucleoprotein; RNA-binding; Spliceosome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U15009; AAA57034.1; -; mRNA EMBL CR456583; CAG30469.1; -; mRNA EMBL AK296173; BAG58909.1; -; mRNA EMBL AB451249; BAG70063.1; -; mRNA EMBL AB451373; BAG70187.1; -; mRNA EMBL AP000356; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471095; EAW59670.1; -; Genomic_DNA EMBL BC000457; AAH00457.1; -; mRNA EMBL BC003150; AAH03150.1; -; mRNA CCDS CCDS13828.1; -. [P62318-1]; . RefSeq NP_001265585.1; NM_001278656.1. [P62318-1]; . RefSeq NP_004166.1; NM_004175.4. [P62318-1]; . UniGene Hs.356549; -; . PDB 1D3B; X-ray; 2.00 A; A/C/E/G/I/K=1-75 PDB 3CW1; X-ray; 5.49 A; D/S/T/U=1-126 PDB 3JCR; EM; 7.00 A; R/r=1-126 PDB 3PGW; X-ray; 4.40 A; W/Z=1-126 PDB 3VRI; X-ray; 1.60 A; C=54-63 PDB 4PJO; X-ray; 3.30 A; A/O/a/o=1-126 PDB 4WZJ; X-ray; 3.60 A; AD/AK/AR/BD/BK/BR/CD/CK/CR/DD/DK/DR=1-126 PDBsum 1D3B; -; . PDBsum 3CW1; -; . PDBsum 3JCR; -; . PDBsum 3PGW; -; . PDBsum 3VRI; -; . PDBsum 4PJO; -; . PDBsum 4WZJ; -; . ProteinModelPortal P62318; -; . SMR P62318; -; . BioGrid 112518; 112; . DIP DIP-31216N; -; . IntAct P62318; 48; . MINT MINT-5002679; -; . STRING 9606.ENSP00000215829; -; . iPTMnet P62318; -; . PhosphoSitePlus P62318; -; . SwissPalm P62318; -; . DMDM 51338667; -; . EPD P62318; -; . MaxQB P62318; -; . PaxDb P62318; -; . PeptideAtlas P62318; -; . PRIDE P62318; -; . TopDownProteomics P62318-1; -. [P62318-1]; . DNASU 6634; -; . Ensembl ENST00000215829; ENSP00000215829; ENSG00000100028. [P62318-1]; . Ensembl ENST00000402849; ENSP00000385266; ENSG00000100028. [P62318-2]; . Ensembl ENST00000404603; ENSP00000456090; ENSG00000100028. [P62318-1]; . GeneID 6634; -; . KEGG hsa:6634; -; . UCSC uc003aam.3; human. [P62318-1]; . CTD 6634; -; . DisGeNET 6634; -; . GeneCards SNRPD3; -; . HGNC HGNC:11160; SNRPD3; . HPA HPA001170; -; . MIM 601062; gene; . neXtProt NX_P62318; -; . OpenTargets ENSG00000100028; -; . PharmGKB PA36001; -; . eggNOG KOG3172; Eukaryota; . eggNOG COG1958; LUCA; . GeneTree ENSGT00610000086153; -; . HOGENOM HOG000182712; -; . HOVERGEN HBG105305; -; . InParanoid P62318; -; . KO K11088; -; . OMA EGHVVTC; -; . OrthoDB EOG091G0ZWE; -; . PhylomeDB P62318; -; . TreeFam TF354302; -; . Reactome R-HSA-109688; Cleavage of Growing Transcript in the Termination Region; . Reactome R-HSA-111367; SLBP independent Processing of Histone Pre-mRNAs; . Reactome R-HSA-191859; snRNP Assembly; . Reactome R-HSA-72163; mRNA Splicing - Major Pathway; . Reactome R-HSA-72165; mRNA Splicing - Minor Pathway; . Reactome R-HSA-77588; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs; . ChiTaRS SNRPD3; human; . EvolutionaryTrace P62318; -; . GeneWiki SNRPD3; -; . GenomeRNAi 6634; -; . PRO PR:P62318; -; . Proteomes UP000005640; Chromosome 22; . Bgee ENSG00000100028; -; . CleanEx HS_SNRPD3; -; . ExpressionAtlas P62318; baseline and differential; . Genevisible P62318; HS; . GO GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB; . GO GO:0000243; C:commitment complex; IBA:GO_Central; . GO GO:0005829; C:cytosol; IDA:UniProtKB; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0034709; C:methylosome; IDA:UniProtKB; . GO GO:0016604; C:nuclear body; IDA:HPA; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0034715; C:pICln-Sm protein complex; IDA:UniProtKB; . GO GO:0071011; C:precatalytic spliceosome; IBA:GO_Central; . GO GO:0071010; C:prespliceosome; IBA:GO_Central; . GO GO:0030532; C:small nuclear ribonucleoprotein complex; TAS:ProtInc; . GO GO:0034719; C:SMN-Sm protein complex; IDA:UniProtKB; . GO GO:0005681; C:spliceosomal complex; TAS:ProtInc; . GO GO:0097526; C:spliceosomal tri-snRNP complex; IBA:GO_Central; . GO GO:0005685; C:U1 snRNP; IDA:UniProtKB; . GO GO:0005689; C:U12-type spliceosomal complex; IDA:UniProtKB; . GO GO:0005686; C:U2 snRNP; IBA:GO_Central; . GO GO:0005687; C:U4 snRNP; IDA:UniProtKB; . GO GO:0005682; C:U5 snRNP; IBA:GO_Central; . GO GO:0005683; C:U7 snRNP; IDA:UniProtKB; . GO GO:0019899; F:enzyme binding; IPI:UniProtKB; . GO GO:0071208; F:histone pre-mRNA DCP binding; ISS:UniProtKB; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0070034; F:telomerase RNA binding; IPI:BHF-UCL; . GO GO:1990446; F:U1 snRNP binding; IEA:Ensembl; . GO GO:0030620; F:U2 snRNA binding; IPI:BHF-UCL; . GO GO:0071209; F:U7 snRNA binding; IPI:BHF-UCL; . GO GO:0008334; P:histone mRNA metabolic process; TAS:Reactome; . GO GO:0000398; P:mRNA splicing; via spliceosome; IC:UniProtKB GO GO:0051170; P:nuclear import; TAS:Reactome; . GO GO:0006479; P:protein methylation; IDA:MGI; . GO GO:0008380; P:RNA splicing; TAS:ProtInc; . GO GO:0000245; P:spliceosomal complex assembly; IBA:GO_Central; . GO GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB; . GO GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome; . CDD cd01721; Sm_D3; 1; . InterPro IPR027141; LSm4/Sm_D1/D3; . InterPro IPR010920; LSM_dom; . InterPro IPR001163; LSM_dom_euk/arc; . InterPro IPR034099; SmD3; . PANTHER PTHR23338; PTHR23338; 1; . Pfam PF01423; LSM; 1; . SMART SM00651; Sm; 1; . SUPFAM SSF50182; SSF50182; 1; .

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